Journal Articles

Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy

https://www.jci.org/articles/view/89820

Use of Topical Calcipotriol Plus 5-Fluorouracil in the Treatment of Actinic Keratosis: A Systematic Review

https://pubmed.ncbi.nlm.nih.gov/35005863/

Skin cancer precursor immunotherapy for squamous cell carcinoma prevention

https://insight.jci.org/articles/view/125476

A review of actinic keratosis, skin field cancerisation and the efficacy of topical therapies

https://onlinelibrary.wiley.com/doi/full/10.1111/ajd.13447

Current Trials

Combination 5-FU / Calcipotriene Cream for SCCIS/SCC

https://clinicaltrials.gov/ct2/show/NCT04839731

Background Reading

Topical Combination Treatment Significantly Reduces Skin Cancer Risk

https://www.uspharmacist.com/article/topical-combination-treatment-significantly-reduces-skin-cancer-risk

CALCIPOTRIENE AND 5-FLUOROURACIL: DERMATOLOGY’S NEW DYNAMIC DUO?

https://www.aad.org/dw/dw-insights-and-inquiries/2019-archive/september/calcipotriene-and-5-fluorouracil

Actinic Keratosis Overview

https://www.skincancer.org/skin-cancer-information/actinic-keratosis/